Alanine Aminotransferase (ALT)

The Alanine Aminotransferase (ALT) blood test measures the level of ALT, an enzyme found primarily in the liver, in your blood. ALT levels can provide valuable information about liver function and the health of your liver cells.

The test is typically performed by taking a blood sample, usually from a vein in your arm, which is then analyzed in a laboratory. ALT levels are reported in units per liter (U/L).

ALT is primarily found within liver cells. When liver cells are damaged or injured, ALT is released into the bloodstream, leading to an increase in ALT levels in the blood. Therefore, elevated ALT levels can indicate liver damage or disease.

The normal range for ALT levels may vary slightly depending on the laboratory and the specific testing method used. However, as a general guideline, normal ALT levels are typically below 40 U/L for men and below 32 U/L for women.

Significantly elevated ALT levels can indicate liver conditions such as hepatitis (inflammation of the liver), liver cirrhosis (scarring of the liver), or liver damage due to alcohol abuse or certain medications. However, it’s important to note that elevated ALT levels can also be caused by factors unrelated to the liver, such as muscle injury or certain medications.

Interpretation of the ALT test results should be done in consultation with a healthcare professional. They will consider your symptoms, medical history, and other factors to make an accurate diagnosis and determine the appropriate treatment plan, if necessary.

If your ALT levels are abnormal, further evaluation may be required to identify the underlying cause of liver damage or disease. This may involve additional blood tests, imaging studies, or liver function tests.

Regular monitoring of ALT levels may be recommended for individuals with known liver conditions or those taking medications that can affect liver function, to assess response to treatment or to detect any potential liver damage.